Ferribacterium limneticum, gen. nov., sp. nov., an Fe(III)-reducing...
Abstract A dissimilatory Fe(III)-reducing bacterium was isolated from mining-impacted lake sediments and designated strain CdA-1. The strain was isolated from a 4-month enrichment culture with acetate...
View ArticleCirculating Ghrelin Levels in Pathophysiological Conditions
AbstractCirculating levels of ghrelin, are regulated by short-term factors pertaining to food ingestion and longer-term factors pertaining to body weight. The short-term, or prandial, regulation is...
View ArticleRole of metabolically active hormones in the insulin resistance associated...
AbstractBackgroundThe mechanisms by which glucocorticoid therapy promotes obesity and insulin resistance are incompletely characterized. Modulations of the metabolically active hormones, tumour...
View ArticleMineralogy Influences Structure and Diversity of Bacterial Communities...
AbstractOur understanding of mineralogical influences on subsurface microbial community structure and diversity has been difficult to assess due to difficulties in isolating this variable from others...
View ArticleA Novel Weight-Reducing Operation: Lateral Subtotal Gastrectomy with Silastic...
AbstractBackground“The ideal bariatric operation should preserve normal gastroduodenal continuity, reduce food intake, and allow the addition of intestinal short-circuiting that would stimulate GLP-1...
View ArticleExpression of obestatin and ghrelin in papillary thyroid carcinoma
AbstractGhrelin and obestatin are two peptide hormones with opposing roles in the control of appetite: orexigenic and anorexigenic, respectively. Loss of appetite is a common, serious complication of...
View ArticleProteogenomic and functional analysis of chromate reduction in Acidiphilium...
AbstractAcidiphilium cryptum JF-5, an acidophilic iron-respiring Alphaproteobacterium, has the ability to reduce chromate under aerobic and anaerobic conditions, making it an intriguing and useful...
View ArticleGastric bypass surgery vs intensive lifestyle and medical intervention for...
AbstractAims/hypothesisMounting evidence indicates that Roux-en-Y gastric bypass (RYGB) ameliorates type 2 diabetes, but randomised trials comparing surgical vs nonsurgical care are needed. With a...
View ArticleMetabolic Surgery in the Treatment Algorithm for Type 2 Diabetes: a Joint...
AbstractBackgroundDespite growing evidence that bariatric/metabolic surgery powerfully improves type 2 diabetes (T2D), existing diabetes treatment algorithms do not include surgical options.AimThe 2nd...
View ArticleMetabolic surgery for the treatment of type 2 diabetes in obese individuals
AbstractSeveral bariatric operations originally designed to promote weight loss have been found to powerfully treat type 2 diabetes, causing remission in most cases, through diverse mechanisms...
View ArticleProspective evaluation of insulin and incretin dynamics in obese adults with...
AbstractAims/hypothesisIn this prospective case–control study we tested the hypothesis that, while long-term improvements in insulin sensitivity (SI) accompanying weight loss after Roux-en-Y gastric...
View ArticleMetabolic surgery for type 2 diabetes
Clinicians note that bariatric operations can dramatically resolve type 2 diabetes, often before and out of proportion to postoperative weight loss. Now two randomized controlled trials formally show...
View ArticleJoint international consensus statement for ending stigma of obesity
AbstractPeople with obesity commonly face a pervasive, resilient form of social stigma. They are often subject to discrimination in the workplace as well as in educational and healthcare settings....
View ArticleSpermiogenesis and exchange of basic nuclear proteins are impaired in male...
AbstractCa2+/calmodulin-dependent protein kinase IV (Camk4; also known as CaMKIV), a multifunctional serine/threonine protein kinase with limited tissue distribution, has been implicated in...
View ArticleMelanocortins and body weight: a tale of two receptors
The phenotypes of mice lacking melanocortin-3 (Mcr3) and melanocortin-4 receptors (Mc4r) demonstrate that these isoforms reduce body weight through distinct and complementary mechanisms. Mc4r regulates...
View ArticleFood alert
The gut prevents nutrient overload during a meal by promoting satiety and enhancing insulin secretion. New findings show that nutrients in the gut also activate a neural circuit that increases insulin...
View ArticleThe coming of age of metabolic surgery
Individuals with obesity who undergo bariatric surgery are much less likely to develop type 2 diabetes mellitus than are those receiving routine care, new findings reveal. Intriguingly, baseline data...
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Evaluation of a Magnetic Compression Anastomosis for Jejunoileal Partial...
AbstractPurposeMetabolic surgery remains underutilized for treating type 2 diabetes, as less invasive alternative interventions with improved risk profiles are needed. We conducted a pilot study to...
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